JOHANNES G. KHINAST
Institute for Process Engineering
Pharmaceutical and Process Engineering
Graz University of Technology
AUSTRIA
Tel: (0316) 873 7978
Email: khinast@tugraz.at
EDUCATION
Graz University of Technology, Austria, Chemical Engineering DI, 1991, highest
distinction
Graz University of Technology, Austria Chemical Engineering Ph.D., 1995,
highest distinction
University of Houston, Houston, TX Chemical Engineering Post Doc, 1/96 -
6/98
POSITIONS
Assistant Professor, Rutgers University, USA, 7/98-6/03
Tenured Professor, Rutgers University, USA, 7/03-present
Director of the Rutgers Catalyst Consortium, Rutgers University, USA, 2003-2006
Marie Curie Chair of the European Union, 2005-2008
Professor of Pharmaceutical and Process Engineering, 2005-present
Head of the Institute for Process Engineering, TU Graz, 2006-present
Scientific Director of the Research Center for Pharmaceutical Engineering,
2008-present
AWARDS AND HONORS
• Erwin Schrödinger Scholarship (Austrian Science Foundation, FWF), 1995
• Distinguished Scholarship from the Austrian Industrial Society, 1995
• Best applied paper in AIChE Journal (SWS), 1999
• Bristol-Myers Squibb Young Faculty Development Award, 1999
• DuPont Young Professor Award, 2000
• North American Mixing Forum Award, 2000
• NSF CAREER Award, 2001
• Arthur and Dorothy Sigel Lecturer, Michigan Tech, 2001
• Early Tenure, 2003
• Offer Institute Head and Professor at the University Stuttgart, 2003
• Best theoretical paper in AIChE Journal (SWS), 2006
• EU Marie Curie Chair, 2005
• Selected University Councelor of Vienna University of Technology
EDUCATION AND TEACHING
• Ph.D. training with Prof. Gernot Staudinger, TU Graz
• Postdoctoral training with Prof. Dan Luss, University of Houston
• Directed research (1998 to 2008):
6 PhD degrees in progress, 10 PhDs graduated
2 past post-doctoral trainees (Dr. Lekhal,
Dr. Vassiliev)
4 current post-doctoral trainees (Dr. Schider, Dr. Kutschera, Dr. Gruber-Wölfler)
40+ undergraduate & diploma thesis
20+ high school students
• Courses taught (1998 to 2008): Fluid Mechanics (undergrad.), Process
Engineering Lab (undergrad.), Reaction Engineering (grad.), Industrial
Chemistry of Drugs
and Fine Chemicals (grad.), Advanced Numerical Methods (grad.), Biochemical
Engineering (undergrad.), Laboratory (undergrad and grad), Research (grad),
Pharmaceutical Engineering I+II (undergrad+grad), Particle Technology I+II
(undergrad + grad)
COLLABORATORS
Prof. Alan Goldman (Rutgers, Chemie), Dr. Tiberiu M. Leib (DuPont), Prof. Michael
P. Harold (Univ of Houston), Prof. Dan Luss (U. of Houston), Prof. Gretar
Tryggvason (Worcester Polytechnical Institute), Dr. San Kiang (Bristol-Myers
Squibb), Dr. Yongkui Sun (Merck and Company), Prof. Harald Raupenstrauch
(TU), Prof. Yves Chabal (Rutgers, Chemistry and Physics), Prof. Karsten Krogh-Jespersen
(Rutgers), Dr. Michael Schlueter (Univ. Bremen), Prof. Marianthi Ierapetritou
(Rutgers), Prof. Ben Glasser (Rutgers), Prof. Fernando Muzzio (Rutgers),
Prof. Zimmer (KFU), Prof. Brenn (TU Graz)
PHD THESIS ADVISOR AND POSTGRADUATE-SCHOLAR SPONSOR
Phd-students past and current:
• Anthony Panarello (graduated, Rutgers)
• Athanas Koynov (graduated, Rutgers)
• Bindal Anditya (graduated, together with Marianthi Ierapetritou, Rutgers)
• Jane Wang (graduated, Rutgers)
• Jodi Raffensberger (graduated, with Ben Glasser)
• Johannes Wurzenberger (graduated, TU Graz, with Harald Raupenstrauch)
• Jeng Shiou (graduated, Rutgers)
• Heidrun Wölfler (graduated, Rutgers)
• Nripen Sharma (graduated, Rutgers, co-advised)
• Stefan Radl (graduate student, TU Graz)
• Alexander Muhr (graduate student, TU Graz)
• Radompon Sungkorn (graduate student, TU Graz)
• Rafael Eder (graduate student, TU Graz)
• Gregor Toschkoff (graduate student, TU Graz)
• Thomas Hörmann (graduate student, TU Graz)
• Brigitte Gübitz (graduate student, TU Graz)
Post Docs past and current:
• Dr. Azzeddine Lekhal (Post Doctoral Researcher with B. Glasser, Rutgers,
now Schering-Plougg)
• Dr. Aleksey Vasiliev (Post Doctoral Researcher, Rutgers)
• Dr. Gerburg Schider (Post Doctoral Researcher, TU Graz)
• Dr. Christoph Kutschera (Post Doctoral Researcher, TU Graz)
• Dr. Pietro Santagati (Post Doctoral Researcher, TU Graz)
• Dr. Heidi Woefler (Post Doctoral Researcher, TU Graz)
• Dr. Vittorio Capello (Post Doctoral Researcher, TU Graz)
PROFESSIONAL ACTIVITIES
American Institute of Chemical Engineers (AIChE)
• AICHE Chair in Various Sessions at National Meetings, 2003-2009
• Member of Scientific Committee ISCRE
• AICHE Chair of Programming Area 20b (Reaction Engineering), 2004-2006
• Scientific Committee NASCRE 2, 2007
• Co-Chair of CFD in Chemical Reaction Engineering, Barga Italy, 2005
• Chair, Session entitled "Unsteady-State Operation of Chemical Rectors",
Annual AIChE Meeting, November 2000, Los Angeles, CA
• Chair, Session entitled "Drying in the Food and Pharmaceutical Industry",
Annual AIChE Meeting, November 2000, Los Angeles, CA
• Chair, Session entitled "Unsteady-State Operation of Chemical Rectors",
Annual AIChE Meeting, November 2001, Reno, NV
• Chair, Session entitled "Unsteady-State Operation of Chemical Rectors",
Annual AIChE Meeting, November 2002, Indianapolis, IN
• Chair, Sessions entitled "In Honor of Dan Luss' 65th Birthday 1&2",
Annual AIChE Meeting, November 2003, San Francisco, CA
Member of AIChE, ACS, ISPE, Catalysis Society of Metropolitan New York
Consultant for Bristol-Myers Squibb, Merck, Energia, DuPont, Schering Plough
Reviewer of Journal Articles, Textbooks, NSF, DOE
• Referee for AIChE Journal, Industrial Engineering and Chemistry Research,
Chemical Engineering Science, Energy and Fuels, Pharmaceutical Technology,
Catalysis Today,
• Textbook reviews for McGraw-Hill
Editor special issue of Chemical Engineering Science on Pharmaceutical Engineering,
2009
RESEARCH INTEREST
Pharmaceutical Engineering: The development of novel methods for the production
of the drugs and formulations of the future is one of the main emphasis of
our work.
Chiral Catalysis: Various methods are studied for heterogenizing of homogeneous
chiral catalysts and for developing new chiral catalysts.
Numerical Analysis and Simulation of Complex Systems: The goal of our research
is to develop numerical methods and bifurcation techniques especially for models
of high dimension by application of direct linearization and operator methods
in combination with novel numerical techniques (front-tracking, domain decomposition,
subspace iteration, multi-level preconditioning, etc.).
PUBLICATIONS IN
REFEREED
JOURNALS & BOOKS
- Khinast J., Staudinger G., (1995), Dynamic Simulation of Reacting Particles,
Scientific Computing I, Springer Verlag, Heidelberg
- Aichinger, G., Brunner,
C., Khinast, J., Seebauer, (1995), Kinetic Studies on Low Temperature,
Dry
Flue Gas Desulphurization, Coal Sci. & Techn.
12, p.124
- Khinast J. Krammer G.F., Brunner Ch., (1996), Decomposition of Limestone:
the Influence of CO2 and Particle Size on the Reaction Rate, Chem. Eng. Sci.
51, 623
- Krammer G.F., Khinast J., Staudinger, (1997), Reaction of Ca(OH)2 with
SO2 at low Temperature, Ind. Eng. Chem. Res, 36, p.1410-1418
- Khinast J., Brunner, Ch.,. Aichinger, G., Staudinger, G, (1995), Reactions
During Low Temperature: Dry Flow Gas Desulphurization, SO2-Control
- Somani M., Viswanath S., Khinast J., Luss D., (1997), Maximum Temperature
in a Reverse-Flow Reactor with two independent reactions, Chem. Eng Sci.
52, 15, p.2483-2495
- Khinast, J., Luss, D., (1997), Mapping Regions with Different Bifurcation
Diagrams of a Reverse Flow Reactor, AIChEJ., 43, 8, p.2034-2047
- Khinast, J., Luss, D., Harold, M.P, Ostermaier, J.J., McGill R., (1998),
Continuously Stirred Decanting Reactor - Operation and Stability Considerations,
AIChEJ., 44, 2
- Khinast, J., Gurumoorthy, A., Luss, D., (1998), Complex Dynamic Features
of a Cooled Reverse-Flow Reactor, AIChEJ., 44,5, p.1128
- Khinast, J., Luss, D, Leib T.M., Harold, M.P., (1998), Boiling slurry
reactor: Feasible operation and stability, AIChEJ. 44, 8, p.1868
- Luss, D. and J. Khinast (1999), Efficient Bifurcation Analysis of Forced
Periodic Processes, Scient. Comp. Chem. Eng., Springer Verlag,Berlin
- Khinast, J. (1999), Numerical Bifurcation Analysis of Chemical Reactor
Models of High Dimension, Proc. Scient. Comp. Chem. Eng., Springer Verlag,Berlin
- Khinast, J., Jeong, Y.O., Luss, D., (1999), Dependence of Cooled Reverse-Flow
Reactor Dynamics on Reactor Model, AIChEJ., 45, 2, 299
- Khinast, J., Luss,
D, Leib T.M., Harold, M.P., (1999), Impact of an Undesired Reaction on
a Boiling Slurry
Reactor", Chem. Eng. Sci., 54,
2295
- Khinast, J., Luss, D, Leib T.M., Harold, M.P., (1999), The Adiabatic
Boiling Slurry Reactor: Influence of Axial Dispersion, Chem. Eng. Sci. 54,
5021
- J. Khinast and V. Balakotaiah, “Numerical Bifurcation Analysis of Chemical
Reactor Models of High Dimension,” p. 1-37, in Numerical Methods for Bifurcation
Problems and Large-Scale Dynamical Systems, E. Doedel and L.S. Tuckerman
(eds.), Springer Verlag, Berlin, 2000
- Khinast, J. and D. Luss, (2000), Efficient Bifurcation Analysis of Periodically-Forced
Distributed Parameter Systems, Comp. Chem. Eng. 24, 139
- Khinast, J.G. (2000), Teaching Kinetics, Catalysis, and Reactor Design
- A Parallel Approach, Chem. Eng. in the New Millennium (R.P. Hesketh, C.S.
Howat, D.S. Dixon, eds.) AIChE, p.133-140
- Garg, R., Luss, D., and J. G. Khinast, (2000), Dynamic and Steady-State
Features of a Cooled Countercurrent Flow Reactor, AIChEJ. 46 (10), 2030
- Lekhal, A., Glasser, B., Khinast J.G., (2001), Impact of Drying on Catalyst
Profile of supported Impregnation Catalysts, Chem Eng. Sci. 56 (15), 4473-4487
- Khinast, J.G. (2001), Impact of 2-D Bubble Dynamics on the Selectivity
of Fast Gas-Liquid Reactions, AIChE J. 47(10), 2304-2319.
- Lekhal, A+., Khinast J.G., Glasser, B., (2001), Predicting the Effect
of Drying on Supported Coimpregnation Catalysts, Ind. Eng. Chem. Res., 40,
3989-3999
- Ierapertitou, M., and J. G. Khinast, (2002), A Novel Sampling Technique
for Efficient Stability Analysis of Chemical Reactors, AIChEJ. (48), 187-192
- Wurzenberger J.C., Wallner S., Raupenstrauch H., and J. G. Khinast,
(2002) Thermal Conversion of Biomass: Comprehensive Reactor and Particle
Modeling,
AIChE J (48), p. 2398-2411.
- Bindal, A., Khinast,
J.G., Ierapetritou, M.G., (2003) Adaptive Multiscale Solution of Dynamical
Systems in Chemical
Processes using Wavelets, Comp & Chem.
Eng. 27, 131-141
- Khinast J.G., Bauer A., Bolz D. and A. Panarello, (2003), Mass Transfer
Enhancement by Static Mixers in a Wall-Coated Catalytic Reactor, Chem. Eng.
Sci. 58, 6, p1063-1070, 2003
- Lekhal, A., Girard, K., Brown, M., Kiang, S., Glasser B. and J.G. Khinast,
(2003) Impact of Agitated Drying on Crystal morphology: KCl-water System,
Powder Technology, 119-130
- Raffensberger J., Koynov A., Glasser B. and J.G. Khinast, Influence
of Particle Properties on the Yield and Selectivity of Fast Heterogeneously
Catalyzed Gas-Liquid Reactions, (2003) International Journal of Reaction
Engineering,
A15
- Panarello, A. and J.G. Khinast (2003), Synthesis of a novel ethylene-bis(tetrahydroindenyl)
ligand containing a functionalized four-carbon tether for heterogenizing
onto solid supports, Tetrahedron Letters, 44, 4095-4098
- Koynov, A. and J.G.
Khinast (2003), Yield and Selectivity of Reactions in Bubble Column Reactors
Operating
in Different Flow Regimes", AIChEJ.
- Khinast, J.G., A. Koynov, and T.M. Leib, (2003), Reactive Mass Transfer
at Gas-Liquid Interfaces: Impact of Micro-Scale Fluid Dynamics on Yield and
Selectivity of Liquid-phase Cyclohexane Oxidation, Chem. Eng. Sci., 58, 3961-3971
- Lekhal A., Girard K. P., Brown, M. A., Kiang S. , Khinast J.G. and B.
J. Glasser, (2004), The Effect of Agitated Drying on Crystal Morphology of
L-Threonine,
Intl. J. of Pharmaceutics, 270, 263-277
- Lee, K.Y., J.J-Y. Lee J., R. Stencel and J.G. Khinast, (2004) Photo-chemical
Remediation of Tetrachloroethylene: Reactor Design, Construction, and Preliminary
Results, J. of Env. Eng., ASCE 130, 1, 100
- Lekhal A., Glasser B.J. and J. G. Khinast (2004), Influence of pH and
ionic strength on the Activity Profile of Impregnation Catalysts, Chem. Eng.
Sci.
59, 1063-1077
- Lee K.Y., Lee J.Y. and J.G. Khinast, (2004) Photochemical destruction
of PCE and TCE from the exhaust of a groundwater remediation air-stripper,
Journal
of Hazardous Materials, p.1265
- Koynov, A. and J.G. Khinast (2004), Effects of hydrodynamics and Lagrangian
Transport on Chemically Reacting Bubble Flows, Chem. Eng. Sci. 59(18) 3907-3927
- affensberger J., Koynov A., Glasser B. and J.G. Khinast, (2004) Analysis
of Heterogeneously Catalyzed Reactions Close to the Gas-Liquid Interface
of Bubbles, AIChE J.51 (5) p.1482-1496
- Wang, J. and J.G. Khinast (2004), Analysis of the Complex Nonlinear
Behavior of Reacting Bubbly Flows, Chem. Eng. Sci., 59, 5575-5585
- Conway S.L., Lekhal A., Khinast J.G., and Benjamin J. Glasser, (2005),
Granular flow and Segregation in A four-bladed mixer, Chem. Eng. Sci. 60,
7091-7107
- Vassylyev O., Panarello A. and J.G. Khinast, (2005) Enantioselective
Hydrogenations with Chiral Titanocenes, Molecules, 10, 518–550
- Panarello, A., Vassylyev, O. and J.G. Khinast, (2005), Preparation of
Derivatized Ethylene-bis-(indenyl) Ligands via homogeneous Suzuki Couplings
on Pd, Tetrahedron
Letters, 46, 1353-1356
- A. Lekhal, B. Glasser and J. Khinast (2005) Drying of supported catalysts,
chapter in Advances in Catalyst Preparation, (ed. Richards, R.), Marcel Dekker
- Panarello, A., Vassylyev O. and J. G. Khinast, (2005) Use of Oxirane
Ring-Opening Reactions for Synthesis of Ethylene-bis(indenyl) Ligands Containing
Alkene
Tethers, SynLett 5, p.797-800
- Koynov, A., Tryggvason G. and J.G. Khinast (2005), Mass Transfer and
Chemical Reactions in Bubble Swarms with Dynamic Interfaces, AIChE J. 51
10, 2786-2800
- G. Viswanathan, A. Bindal, J. Khinast and D. Luss, (2005), Stationary
transversal hot zones in adiabatic packed bed reactors, AIChEJ. 51, 11, 3028-3038
- Langner, A., Panarello, A., Rivillon, S., Vassylyev, O., Khinast, J.G.
and Y.J. Chabal, (2005), Controlled Silicon Surface Functionalization by
Alkene Hydrosilylation, JACS 127, 37, 12798 – 12799
- Vassylyev, O., Chen, J.-S., Panarello A., and J. G. Khinast (2005),
Catalytic Properties of Several Supported Pd(II) Complexes for Suzuki Coupling
Reactions,
Tetrahedron Letters 46, 40, 6865-6869
- Khinast, J.G., (2005), Mikromischer in Deformierbaren Blasenschwaermen,
Chemie Ingenieur Technik, 77, 11, p 1750-1763
- Koynov A., and J.G. Khinast, (2005), Micromixing in Bubble Swarms, Chemical
Engineering and Technology 77, p.13-23.
- Vassylyev, O., Hall, G. and J.G. Khinast, (2006), Modification of Zeolite
Surfaces by Grignard Reagent, J. Porous Materials 13, 1, p.5-11
- Lekhal A., Conway S., Glasser B.J. and J.G. Khinast (2006), Characterization
of Granular Flow of Wet Solids in a Bladed Mixer, AIChEJ. 52, 8, 2757-2766
- Koynov, G. Tryggvason,
M. Schlüter, and J. G. Khinast. "Mass Transfer
and Chemical Reactions in Reactive Deformable Bubble Swarms." Applied
Physics Letters 88 (2006), 134102
- Panarello, A., Vassylyev, O. and J.G. Khinast, (2006), Efficient Surface
Functionalization of Zeolites via Esterification, J. of Microporous and Mesoporous
Materials 92 (1-3,) 101-108
- Raffensberger, J., Glasser, B.J. and Khinast, J.G., Effect of Droplet
Wake Phenomena on Mixing-Sensitive Pharmaceutical Reactions, Pharm. Tech.,
30:11,
66-79, (2006).
- Lee, K. Y., J.G. Khinast and J. H. Kim (2007), Numerical modeling of
contaminant transport resulting from dissolution of a coal tar pool in an
experimental
aquifer, Hydrogeology 15 (4), p. 705-714, DOI 10.1007/s10040-006-0144-y.
- Chen, J.S. O N. Vassylyev, A. P. Panarello, and J. G. Khinast, (2007),
Pd-Leaching and Pd-Removal in Pd/C-Catalyzed Suzuki couplings, Journal of
Applied Catalysis A: General, Volume 325, Issue 1, (30), 76-86
- Vasiliev A., LV. Golovko, V.A. Povazhny, E. Zlotnikov, J. Chen and J.
G. Khinast, (2007) Functionalized nanoporous carbon as a catalyst for pharmaceutical
Suzuki coupling reactions, Microporous and Mesoporous Materials, 101, Issue
3, 342-347
- Radl S. Tryggvason, G. and J.G. Khinast, (2007), Flow and Mass Transfer
of Fully Resolved Deformable Bubble Swarms in non-Newtonian Fluids, AIChE
J. 53 (2007) 7 , p 1861 - 1878
- Koynov A., Tryggvason G., and J.G. Khinast, (2007), Characterization
of the localized hydrodynamic shear forces and dissolved oxygen distribution
in
sparged bioreactors, Biotechnology and Bioengineering 92 (2), p.317-331
- Radl S. and J.G. Khinast, (2007), Prediction of mass transfer coefficients
in non-Newtonian fermentation media using first-principles methods, Biotechnology
and Bioengineering 97 (5), p. 1329-1334.
- Vasiliev A., LV. Golovko, V.A. Povazhny, E. Zlotnikov, J. Chen and J.
G. Khinast, (2008) Functionalized nanoporous carbon as a catalyst for Suzuki
coupling
reactions, Microporous and Mesoporous Materials, 101, p. 342-347
- Woelfler H., Flock
M., Sassmanshausen J., and J.G. Khinast, (2008) "The
Structure-Function-Performance Relationship of Bis(cyclopentadienyl)-Based
Group 4 Metallocenes - A DFT Study", Organometallics, 27 (2008), p.
5196-5202.
- Khinast JG., Vasiliev A.N., Zlotnikov E., Riman R., (2008), Chemisorption
of silane compounds on hydroxyapatites of various morphologie, Scripta Materialia,
58, p. 1039 - 1042
- Radl, S.; Koynov, A.; Tryggvason, G.; Khinast, J. (2008), DNS-based
Prediction of the Selectivity of Fast Multiphase Reactions: Hydrogenation
of Nitroarenes.
- Chemical Engineering Science 63 (2008) , p. 3279 - 3291
- Gruber-Wölfler, H.; Rivillon, S.; Chabal, Y. J.; Schitter, G.; Polo,
E.; Ringwald, M.; Khinast, J., (2008), UV-Induced Immobilization of Tethered
Zirconocenes
on H-terminated Silicon Surfaces., Chemical Communications 11, p. 1329 -
1331
- Vasiliev, A.N., Zlotnikov, E., Khinast, J.G. and R.E. Riman, (2008),
Chemisorption of silane compounds on hydroxyapatites of various morphologies.
Scripta materialia
58, 1039 – 1042
- Chen, C.-S., Krogh-Jespersen, K. and J.G. Khinast, (2008) Base- and
Ligand-free Heterogeneously Catalyzed Homocoupling of Arylboronic Acids.
Journal of Molecular
Catalysis / A 285, 14 – 19
- Jeanquartier, C., Schider, G., Feichtenhofer, S., Schwab, H., Schennach,
R., Stettner, J., Winkler, A., Gruber-Woelfler, H., Schitter, G., Eder, R.
J. P. and J.G. Khinast, (2008) A Two-step Method to Covalently Bind Biomolecules
to Group-IV Semiconductors: Si(111)/1,2-Epoxy-9-decene/Esterase, Langmuir
24 (24), p. 13957-13961
- Remy, B., Khinast, J.G., Glasser, B.J., (2008) Discrete Element Simulation
of Free Flowing Grains in a Four-Bladed Mixer, AIChE J, accepted
- Xue, L, Khinast J.G. and B. J. Glasser (2008), A parametric investigation
of impregnation and drying of supported catalysts, Chemical Engineering Science
63 (18), 4517-4530
- Vasiliev, A., Golovko, L., and V. V. Trachevsky, Gene S. Hall, Johannes
G. Khinast (2008), Adsorption of heavy metal cations by organic ligands grafted
on porous materials, Microporous and Mesoporous Materials, 118 (1-3), 251-257
- Radl, S., Kalvoda, E., Glasser, B.J., Khinast, J.G., (2009) Mixing Characteristics
of Wet Granular Matter in a Bladed Mixer, Powder Technology, submitted
- Remy, B., Khinast, J.G., Glasser, B.J., (2009) The Effect of Mixer Properties
and Fill Level on Granular Flow in a Four-Bladed Mixer, AIChE J, 55 (8),
2035-2048
- Vasiliev, A. N., Gulliver,
E. A., Khinast, J. G., Riman, R. E. (2009) Highly dispersible polymer-coated
silver nanomaterial, Elsevier Surfyce & Coating
Techologies, in press.
- Radl S., Suzzi D., and J.G. Khinast, (2009) Mixing in Bubble Swarms,
submitted to AIChE J
- Gruber-Woelfler H., Flock, M., Saßmannshausen, J., Khinast, J. (2009)
The Structure-Function-Performance Relationship of Bis(cyclopentadienyl)-Based
Group 4 Metallocenes - A DFT Study, Organometallics, 27, 5196-5202
- Gruber-Woelfler, H., Eder, R.J.P., Pflueger, I. Wilding, B., Polo,
E., Wagner, J., Khinast, J. G., (2009) Development of a Heterogeneous
EBI-based Titanocene Catalyst for the Hydrosilylation of Imines, Chem.
Commun., submitted
- Gruber-Woelfler, H.; Flock, M.; Fischer, R. C.; Sassmannshausen,
J.; Stanoeva, T.; Gescheidt, G.; Khinast, J. G. (2009) Titanocene
Catalyzed Hydrosilylation of Imines: Experimental and Computational Investigations
of the Catalytic
Active
Species, Organometallics 28, 2546-2553
- Radl S., Tritthart T. and J.G. Khinast, (2009) A Novel Design
for Hot-Melt Extrusion Pelletizers, accepted Chemical Engineering
Science
- Suzzi D., Radl S., J.G. Khinast, (2009) Modeling of the Spray-Particle
Interaction of Rotary Drum Coaters (2009), submitted to Chemical
Engineering Science
- Radl, S.; Suzzi, D.; Khinast, J.: Assessment of Micro- and
Mesomixing in Bubble Swarms via Simulations. - in: Chemical
engineering transactions
17 (2009)
, S. 507 - 512
- Suzzi, D.; Radl, S.; Khinast, J.: Validation of Euler-Euler
and Euler-Lagrange Approaches in the Simulation of Bubble
Swarms. - in:
Chemical engineering
transactions 17 (2009) , S. 585 - 590
- Roblegg E., Schrank S., Griesbacher M., Radl S., Zimmer
A., Khinast J, (2009) Development of disintegrating pellet
formulations
based
on Ludiflash®, submitted to European Journal of Pharmaceutical
Sciences
- Radl, S.; Brandl, D.; Heimburg, H.; Khinast, J.: Granular Flows - How
Size
Matters. - in: Tagungsband (2009), S. 38 – 41 Minisymposium Verfahrenstechnik.
9 papers are currently in preparation and will be submitted in 2009:
- Continuous crystallization
in a tubular crystallizer (Eder & Khinast)
- Novel simulation tool of a spray dryer (Suzzi and Khinast)
- Ontologies and FMEA for Quality by Design (Gübitz and Khinast)
- Advanced bioreactor modelling via Lattice Boltzmann Methods 1 (Santagati
and Khinast)
- Advanced bioreactor modelling via Lattice Boltzmann Methods 2 (Sungkorn,
Radl and Khinast)
- Modeling of Particle-Fluid Interactions (Radl, Suzzi, Khinast)
- Mixing in non-Newtonian Fluids (Hörmann, Suzzi and Khinast)
- Euler-Euler Modeling of Reactive Transport in Fluid-Fluid Systems
(Suzzi, Khinast)
- Comprehensive Modeling of Rotary Drum Coaters including
DEM, particle modelling and air simulation (Suzzi, Toschkoff
and Khinast)
CONFERENCE PROCEEDINGS AND PUBLICATIONS IN NON-REFEREED PUBLICATIONS
> 100
INVITED TALKS
> 50
PRESENTATIONS AND TALKS:
> 150
Funding & Grants
Responsible total Funding
last 5
years: > 28 million Euros
Selected grants:
| 09/06- 08/09 |
FWF (Austrian Science Foundation)
PI: J. Khinast
Amount: approx. $350,000
Title: Development of Heterogeneous Transition Metal Catalysts for Pharmaceutical
Reactions |
| 01/07- 12/10 |
FWF (Austrian Science Foundation)
PI: J. Khinast
Amount: approx. $340,000
Title: Bubble Swarms and Reactive Mass Transfer at Dynamic Interfaces
|
| 07/08- 06/15 |
FFG, SFG and Company Partners
PI: J. Khinast (scientific director and leader of the consortium)
Amount: approx. $ 44 million
Title: Research Center for Pharmaceutical Engineering |
Other grants: Ortner Reinraum Technik, Sandoz, Roche, etc.